Fly-half Will Reed will make his first appearance of the season when Dragons RFC face Cell C Sharks in the United Rugby Championship at Rodney Parade on Saturday.
The Men of Gwent make a total of three changes to the side that defeated Munster Rugby in the first game of the season on home soil last weekend.
Reed is the only change to the back line, with JJ Hanrahan ruled out of the game as a precaution after picking up a knock in training. Hanrahan is expected to be fit for Round 4.
Lock Ben Carter is recalled to partner captain Will Rowlands in the second row. Carter’s return sees George Nott move into the back row to occupy the blindside flanker jersey.
The final change is a first start of the season for Wales international hooker Elliot Dee, with Bradley Roberts moving to the bench.
The return of lock Joe Davies is the only other change among the replacements.
Head Coach Dai Flanagan said: “Sharks will be physical and there is a lot of quality in their side. We need to make sure we match the physicality they bring and stay true to ourselves.
“It was a big result and performance by us against Munster last time out. Now we must replicate it, match it and ensure we get better week by week.
“We need to step forward as a squad again and if we you stay true to ourselves, work hard, we'll be in this fight together.”
Dragons RFC: 15. Angus O’Brien, 14. Rio Dyer, 13. Sio Tomkinson, 12. Jack Dixon, 11. Ashton Hewitt, 10. Will Reed, 9. Rhodri Williams, 8. Ross Moriarty, 7. Taine Basham, 6. George Nott, 5. Will Rowlands (c), 4. Ben Carter, 3. Lloyd Fairbrother, 2. Elliot Dee, 1. Aki Seiuli. Replacements: 16. Bradley Roberts, 17. Rob Evans, 18. Chris Coleman, 19. Joe Davies, 20. Aaron Wainwright, 21. Lewis Jones, 22. Max Clark, 23. Jordan Williams.