| Results Week Ending - 05 June 2022 | ||
| 1stXV | ||
| Central Region | ||
| Eastern Cape | ||
| Daniel Pienaar | 15-40 | Pearson |
| Framesby | 43-07 | Brandwag Uitenhage |
| Graeme College | 31-00 | Ithembelihle |
| Marlow | 51-14 | Hudson Park |
| Port Rex | 32-22 | Cambridge |
| Queen's College | 20-08 | St Andrew's |
| KwaZulu Natal | ||
| Clifton | 19-15 | St Davids |
| Hilton | 29-28 | Glenwood |
| Kearsney | 20-31 | Maritzburg College |
| Northwood | 14-36 | DHS |
| St Charles | 71-00 | Voortrekker PMB |
| Westville | 21-31 | Michaelhouse |
| Noordvaal | ||
| Affies | 21-06 | Menlopark |
| Alberton | 26-12 | Dr Malan |
| Allen Glen | 53-00 | Goudrif |
| Allen Glen | 45-11 | Glenharvie |
| Bastion | 49-14 | Riebeeckrand |
| Brits | 11-23 | Vryburg |
| Carletonville | 67-00 | Alberton |
| Cornwall Hill | 46-07 | Benoni |
| Curro Nelspruit | 37-06 | Bergvlam |
| Die Wilgers | 36-14 | Gerrit Maritz |
| Dinamika | 15-06 | St Benedict's |
| Ellisras | 55-07 | Piet Potgieter |
| Erasmus | 29-31 | CR Swart |
| Eric Louw | 51-26 | Stanford Lake |
| Ermelo | 26-12 | Witbank HTS |
| Frikkie Meyer | 72-00 | Tom Naude |
| Hans Strijdom | 25-22 | Ben Viljoen |
| Heidelberg Volkies | 12-12 | Oos Moot |
| Helpmekaar | 12-26 | EG Jansen |
| Heronbridge | 31-23 | Krugersdorp |
| Hugenote Springs | 26-33 | Klerksdorp |
| Kanonkop | 34-00 | Oosterland |
| Kempton Park | 19-14 | Montana |
| King David Linksfield | 15-12 | Trinityhouse |
| Leeuwenhof | 15-25 | Brandwag |
| Linden | 75-06 | Jan Vijoen |
| Lydenburg | 39-12 | Baberton |
| Marais Viljoen | 10-13 | Ligbron |
| Middelburg | 40-00 | Ben Vorster |
| Noordheuwel | 44-07 | Middelburg HTS |
| Oosterlig | 31-07 | Driehoek |
| Piet Retief | 37-10 | Pionier |
| Potch Volkies | 05-07 | Pietersburg |
| Pretoria Boys High | 17-27 | St John's |
| Randburg | 31-31 | Potch Gim |
| Randpark | 28-00 | Krugersdorp |
| Sasolburg HTS | 20-17 | Delmas |
| St Alban's | 31-21 | Northcliff |
| St Stithians | 07-62 | Jeppe |
| Standerton | 47-21 | Hoogenhout/Genl Hertzog |
| Tuine | 20-32 | Midstream College |
| Warmbad | 78-12 | Northern Academy |
| Waterkloof | 07-34 | Garsfontein |
| Wonderboom | 20-18 | John Vorster HTS |
| Zwartkop | 28-38 | Rustenburg |
| Western Cape | ||
| Bishops | 07-14 | Boland Landbou |
| Boishaai | 42-24 | Wynberg |
| Curro Durbanville | 37-00 | Generations |
| Durbanville | 03-52 | Oakdale |
| Hottentots Holland | 22-23 | Parel Vallei |
| Labori | 27-15 | Bonnievale |
| Milnerton | 26-33 | Brackenfell |
| Paarl Gim | 66-13 | SACS |
| Paul Roos | 12-24 | Rondebosch |
| Tygerberg | 25-35 | Drostdy HTS |
| Bellville | 48-07 | Primrose |
| Melkbosstrand | 10-12 | Hamlets |
| Die Wilgers | 20-12 | Erasmus |
| Die Wilgers | 87-00 | Rietondale |
| Die Wilgers | 13-10 | John Vorster HTS |
| Die Wilgers | 24-17 | Heronbridge |
| Die Wilgers | 31-18 | Curro Hazeldean |
| Die Wilgers | 33-08 | Sutherland |
| Die Wilgers | 36-14 | Gerrit Maritz |