Several teams have already booked their safe passage to the next stage, while others head into the final matches of the Pool campaign needing positive results to boost their chances of advancing.
Which teams have qualified?
Montpellier Hérault Rugby (Pool 2): Winners of the competition in 2016 and 2021, Montpellier Hérault Rugby will be eyeing a third success in the competition this season and secured their Round of 16 berth with wins over Newcastle Falcons, Ospreys and Emirates Lions.
Benetton Rugby (Pool 2): Beaten semi-finalists last season in the EPCR Challenge Cup, Benetton Rugby advanced to the knockout stage for the fourth successive season thanks to triumphs over USAP and Newcastle Falcons.
Emirates Lions (Pool 2): Quarter-finalists last season, Emirates Lions will be eager to advance further this campaign and have qualified for the knockout stage following wins over USAP and Newcastle Falcons.
Ospreys (Pool 2): There will be Welsh representation in the EPCR Challenge Cup Round of 16 as Ospreys have secured their berth with victories over Benetton Rugby and USAP.
Gloucester Rugby (Pool 3): The two-time EPCR Challenge Cup winners have booked their ticket for the Round of 16 with victories over Black Lion, ASM Clermont Auvergne and Edinburgh Rugby.
EPCR Cup qualification FAQ
How many clubs qualify for the knockout stage?
The four highest-ranked clubs in Pool 1, the four highest-ranked clubs in Pool 2, the four highest-ranked clubs in Pool 3 and the fifth-ranked clubs from each of the four Investec Champions Cup Pools will qualify for the Round of 16.
How does home allocation work for the knockout stage?
All clubs will thereafter be ranked in descending order based firstly on their ranking in their pool and subsequently on the number of match points they have accumulated, to create an overall ranking from 1 to 16.
The pool winners will be ranked 1 to 3, the second-placed clubs will be ranked 4 to 6, the two highest-ranked third-placed clubs will be ranked 7 and 8, the qualifying Investec Champions Cup clubs will be ranked 9 to 12, the remaining third-placed club will be ranked 13, and the fourth-placed clubs will be ranked 14 to 16.
The number 1-ranked club will play the number 16-ranked club, number 2 will face number 15, and so on, with the higher-ranked team hosting.
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